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Searchlight

Searchlight provides vital information regarding new therapies and those in the pipeline. It presents relevant and easily digestible information on study results of our own clinical trials, articles on other AIDS-related subjects, commentary from prominent national doctors and scientists, as well coverage of other ARA-related developments.

Current Issue: Winter 2007 issue of Searchlight

Winter 2007
Searchlight - Winter 2007
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Featured in this issue:

The Challenge of Emptying The HIV Reservoir

HIV Viral Reservoirs: Barriers to a Cure
by Dr. Marjan Hezaeh, Ph.D.

Measuring the HIV Reservoir
by Dr. Stephen J. Brown, M.D.



Past Searchlight Issues:

Winter 2007
Searchlight - Summer 2007
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Featured in this issue:

Immunotherapies - Strengthening the Body's Own Defenses

Therapeutic Vaccines: An Alternative Strategy to Contain HIV Infection
by Dr. Marjan Hezaeh, Ph.D.

Immunotherapies For HIV
by Dr. Bernice Schacter, Ph.D.


Fall 2006
Searchlight - Fall 2006
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Featured in this issue:

HIV PREVENTION RESEARCH TIED DOWN BY CONTROVERSY

Are We Ready For PrEP?
by Dr. Joep M. A. Lange

The Logic Behind Treatment Recommendations for the Newly Infected
by Dr. Stephen J. Brown


Spring 2006
Searchlight - Spring 2006
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Featured in this issue:

VACCINE ISSUE

Still Shooting in the Dark?
by Jon Cohen

How Does the US Fund HIV Vaccine Research?
by Bernice Schacter, Ph.D.


Winter 2005

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Featured in this issue:

MICROBICIDES ISSUE

Microbicides Offer Hope as HIV Prevention Tools That Are Under Individual Control
by Dr. Marjan Hezareh

Viral Load Measurements: The Log Scale
by Dr. Stephen J. Brown


Spring 2005

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Featured in this issue:

Highlights from the 12th Conference on Retroviruses and Opportunistic Infections
by Dr. Marjan Hezareh

ARA's Director of Scientific Communications Marjan Hezarah, Ph.D. reviews the latest scientific, therapeutic and clinical data presented at the 12th Conference on Retroviruses and Opportunistic Infections, held in Boston, Massachusetts in Februarry, 2005.

Metabolic Disorders Secondary to HIV Infection and Antiretroviral Treatment - Part II
by Dr. Stephen J. Brown

ARA's Medical Director Stephen J. Brown, M.D. reviews some of the latest studies and recommendations to prevent and treat HIV-related metabolic disorders, including lipodystrophy, in this second installment of a two-part series. We provide an update on our progress in developing the antiviral prostratin.


Fall 2004

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Featured in this issue:

Highlights from the XVth International AIDS Conference in Bangkok
by Dr. Stephen J. Brown

ARA's Medical Director Stephen J. Brown, M.D. reviews in this short report the latest scientific, therapeutic and clinical data presented at the XVth International AIDS Conference (July, 2004) held in Bangkok, Thailand.

Is Injectable Silicone a Safe and Effective Treatment of HIV-associated Facial Lipoatrophy?
by Dr. Marjan Hezareh

ARA's Director of Scientific Communications Marjan Hezarah, Ph.D. reviews and compares various treatment options for the correction of facial lipoatrophy to the latest results obtained on the safety and efficacy of treatment with microdroplet silicone injections.

We provide an update on our progress in developing the antiviral prostratin.


Spring 2004

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Featured in this issue:

Metabolic Disorders Associated with HIV and its Treatment Part I: Lipodystrophy, Etiology, Relationship to HAART and HAART Regimen Considerations
by Stephen J. Brown, M.D.

ARA's Medical Director Stephen J. Brown, M.D. discusses HIV-related lipodystrophy, excercise specialist Noah Manne discusses the importance of diet and exercise for the immune-compromised, and ARA's Director of Scientific Communications Marjan Hezarah, Ph.D. takes a look at some of the briefs from the 11th Conference on Retroviruses and Opportunistic Infections. A new study being conducted at ARA is also announced. We provide an update on our progress in developing the antiviral prostratin.


Summer 2003

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Featured in this issue:

HIV-related Peripheral Neuropathy: Diagnosis and Treatment
by Seymour Young, M.D.

Noted neurologist and member of ARA's Institutional Review Board Seymour Young, M.D. discusses HIV-related peripheral neuropathy. ARA's Director of Scientific Communications Marjan Hezarah, Ph.D. looks at results in some recent HIV/AIDS studies. Four new studies being conducted at ARA are also announced.

We provide an update on our progress in developing the antiviral prostratin.


Spring 2003

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Featured in this issue:

New and Promising Drugs in Devlopment Versus Rising Number of New HIV Infections in U.S.
by Marjan Hezareh, Ph.D.

ARA's Director of Scientific Communications discusses information from the 10th Conference on Retroviruses and Opportunistic Infections In Boston. Marjan also looks at “RNA Interference: A New Tool in the Fight against HIV/AIDS.” Thrree new studies to be conducted at ARA are announced.

We provide an update on our progress in developing the antiviral prostratin.


Fall 2002

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Featured in this issue:

HIV RESERVOIR ISSUE

HIV-1: The Nature of Viral Reservoirs
by Robert Siliciano, M.D., Ph.D.

Robert Siliciano of John Hopkins University discusses the significance of viral reservoirs in eradicating HIV and assesses the likelihood of cleaning out or "flushing" these reservoirs.

ARA's Searchlight Editor Marjan Hezareh discusses reservoirs and also gives us her report on the 2002 XIV International AIDS Conference in Barcelona.

We provide an update on our progress in developing the antiviral prostratin.


Spring 2002

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Featured in this issue:

HIV OVERVIEW ISSUE

HIV-1: Two Decades of Clinical and Scientific Advances
by Marjan Hezareh, Ph.D.

ARA's Searchlight Editor Marjan Hezareh, Ph.D. looks at twenty years of HIV/AIDS research and drug development, assesses where we are now, and takes a look at some new antiviral drugs in the pipeline.

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Fall 2001

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Featured in this issue:

VACCINE & PREVENTION ISSUE

A Boosted Hope: AIDS Vaccine Research
by Marjan Hezareh, Ph.D.

ARA's new Director of Scientific Communications and Searchlight Editor Marjan Hezareh, Ph.D. looks at the challenges faced by the scientific community in developing an effective HIV/AIDS vaccine. Marjan also reports on vaccine developments reported at the March Keystone Conference and the recent "AIDS Vaccine 2000" Symposium in Philadelphia.

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Spring 2001

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Featured in this issue:

Prostratin: A Potential Adjuvant Therapy for HAART Against HIV-1 Reservoirs
by Stephen J. Brown, M.D.

ARA's Director of Clinical Research looks at the unique anti-HIV properties of prostratin, a compound derived from a plant native to Western Samoa.

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Fall 2000

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Featured in this issue:

Achy Breaky HAART
by Linda Grinberg

Structured Treatment Interruptions (STIs) are discussed by Linda Grinberg, President of the Foundation for AIDS & Immune Research and a member of the Board of Directors of Project Inform.

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Spring 2000

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Featured in this issue:

AVN, a Potentially Serious Bone Disorder—
Is the incidence rising in HIV+ people?

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Winter 1999/2000

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Featured in this issue:

HIV Vaccine Development—
The Hurdles Faced by Scientists

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Fall 1999

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Featured in this issue:

Natural immunity to HIV?

Understanding the reasons why some individuals exposed to HIV remain uninfected should shed light on the nature of protective immunity against HIV.

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Drug Resistance Profiles in Tissues

Study Results presented at the 3rd International Workshop on HIV Drug Resistance and Treatment Strategies in San Diego.

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Summer 1999

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Featured in this issue:

Acupuncture for Treating Neuropathy

Making sense of the science: acupuncture therapy was recently evaluated in a large, randomized placebo-controlled clinical trial.

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HIV Neuropathies

Several disorders, no proven treatments.

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Spring 1999

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Featured in this issue:

Mucosal biopsy study results presented in Chicago

AIDS Research Alliance collaborative effort bears fruit Abstract presented at the 6th Conference on Retroviruses and Opportunistic Infection in Chicago.

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Is Sterilizing Immunity Necessary to Prevent HIV Disease?— Interview with Bob Gallo

Dr. Robert Gallo is co-discoverer of the HIV virus and Director of the Institute of Human Virology in Baltimore, MD.

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Is Sterilizing Immunity Necessary to Prevent HIV Disease?— Interview with Neal Nathanson

Dr. Neal Nathanson is the Director of the Office of AIDS Research, the office responsible for setting the scientific agenda for AIDS research at the National Institutes of Health.

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Winter 1998/1999

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Featured in this issue:

The Gut Reaction to HIV

Gut tissue is uniquely vulnerable to HIV, and careful investigation of the gut is likely to provide valuable clues to the pathology underlying HIV infection.

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XQ-9302 Study Report

Report on a Phase I/II study evaluating a compound comprised of twenty uncharacterized Chinese botanicals in HIV-1 infected individuals.

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Summer/Fall 1998

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Featured in this issue:

Clinical Trials to Clinical Reality

"Bridging the gap" between science and the patient.

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